|Ahcène Boumendjel |
04 76 635 311
Drug Design, Drug Synthesis, Natural Products, Membrane Proteins, Nucleic Acids, Epigenetic, From hit to lead, Cancer, Infectious Diseases, Chemical Tools, Chemical Biology
ACTIVITES DE RECHERCHE / SERVICES
The MEDCHEM research activities are focused on drug discovery and development for targeting major human lethal diseases: cancer, infectious diseases and neurodegenerative disorders. Our know-how is drug synthesis and optimization of hit compounds to bring them to first stages of preclinical studies. In the oncology field, we work on the synthesis and development of drug candidates acting as modulators of membrane proteins involved in the multidrug resistance phenotype or as epigenetic inhibitors. Beside, we focus part of our activity on the development of uncharged cyclopeptides as transmembrane vectors of anticancer drugs.
COMPETENCES / MOYENS TECHNIQUES
The DPM has its own chemical library which has been integrated into that of the ICMG, the federative institute that groups together the chemical laboratories on the site of the University Grenoble Alpes.
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UMR 5063 Département de Pharmacochimie Moléculaire (DPM)
Univérsité Grenoble Alpes
470 Rue de la Chimie